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Blood Disorder

Sickle Cell Anemia

An inherited blood disorder common in Central India — with the right treatment and care, sickle cell patients can lead near-normal lives.

Dr. Anil Singhvi

Dr. Anil Singhvi, MD · 35+ years · Founded Madhya Pradesh's first hematology centreConsult in person in Indore, or by video call.

About Sickle Cell Anemia

In sickle cell anemia, an inherited change in haemoglobin makes red blood cells stiff and sickle-shaped. These cells block small blood vessels and break down early, causing anemia, episodes of severe pain (crises), and gradual organ damage. The condition is particularly common in parts of Madhya Pradesh and Central India.

Modern management has changed the outlook completely. Simple, inexpensive medicines like hydroxyurea dramatically reduce pain crises and complications, and with regular follow-up most patients study, work, and raise families like anyone else.

Common symptoms

  • Episodes of severe pain in bones, chest, or abdomen (sickle crises)
  • Chronic anemia — tiredness, pallor, breathlessness
  • Yellowness of eyes (jaundice)
  • Swelling of hands and feet in children
  • Frequent infections and delayed growth
Neha, a sickle cell anemia patient, with Dr. Singhvi
Patient Story

Neha: in our care since she was four

Neha first came to Dr. Anil with sickle cell anemia in 1996, when she was just four years old. With regular follow-up and day-care transfusions when needed, she has grown up, studied and built her life, and she recently celebrated her 34th birthday with us.

1996First visit, age 4
30 yearsOf continuous care

How it is diagnosed

Diagnosis is confirmed with a simple blood test called haemoglobin electrophoresis (or HPLC), which identifies sickle haemoglobin. Family screening is important, and premarital or antenatal counselling helps couples understand the risk to children.

How it is treated

Treatment includes hydroxyurea to reduce crises, folic acid, prompt treatment of pain and infections, vaccination, and blood transfusion when needed. Patients do best with regular monitoring and a clear plan for managing crises early. We provide complete sickle cell care, including day-care transfusion, and have helped patients remain crisis-free for years.

This information is for general education and is not a substitute for a consultation. Every patient is unique — the right treatment can only be decided after proper evaluation.

Watch: Sickle Cell Anemia explained

सिकल सेल का इलाज हुआ आसान

Better treatment options for sickle cell anemia, explained by Dr. Anil.

माँ-बेटे — दोनों का सिकल सेल ठीक!

A mother and son both living normal lives after treatment.

Patient story

No hospital visit since starting treatment

“He is much better now and goes to school regularly. He has not needed a hospital visit since then, and no blood transfusions either.”

— Parent of Tanishk Vishwakarma · Sickle cell anemia

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